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Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum.

<h4>Background</h4>The study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection. Small animal models that support the development of adult parasites have not been identified.<h4>Methodology/princ...

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Autori principali: John B Patton, Sasisekhar Bennuru, Mark L Eberhard, Jessica A Hess, April Torigian, Sara Lustigman, Thomas B Nutman, David Abraham
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2018-12-01
Serie:PLoS Neglected Tropical Diseases
Accesso online:https://doi.org/10.1371/journal.pntd.0006977
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