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IBS stress reactivity phenotype is associated with blood transcriptome profiles and microstructural and functional brain changes

Evidence suggests significant interindividual differences in stress reactivity (SR), but mechanisms and therapeutic implications of these differences are poorly understood. The aim of this study was to identify the biological basis of increased SR by investigating associations between a psychometric...

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Kaydedildi:
Asıl Yazarlar: Jennifer S. Labus, Desiree R. Delgadillo, Steve Cole, Chencai Wang, Swapna Joshi, Arpana Church, Bruce Naliboff, Lin Chang, Jonathan P. Jacobs, Benjamin M. Ellingson, Emeran A. Mayer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2026-06-01
Seri Bilgileri:Neurobiology of Stress
Konular:
Stress reactivity
CREB transcription
Proinflammatory genes
Diffusion tensor imaging
Functional brain connectivity
Irritable bowel syndrome
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2352289526000275
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