STING agonist diABZI confers protection against swine acute diarrhea syndrome coronavirus in neonatal mice by activating antiviral immunity

ABSTRACT The recently identified alphacoronavirus swine acute diarrhea syndrome coronavirus (SADS-CoV) has a high fatality rate in neonatal piglets. Currently, no vaccines or treatment strategies for SADS-CoV infection are available. The stimulator of interferon genes (STING) pathway plays a critica...

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Hlavní autoři:	Yuying Li, Wei Chen, Xinyu Zhang, Jiyong Zhou, Yanqing Hu, Yimin Zhou, Tian Lan, Haixin Huang, Lulu Xie, Yan Qin, Lin Zhou, Wenchao Sun, HuiJun Lu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2026-02-01
Edice:	Journal of Virology
Témata:	swine acute diarrhea syndrome coronavirus (SADS-CoV) STING pathway interferon innate immune response
On-line přístup:	https://journals.asm.org/doi/10.1128/jvi.01703-25
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