Water Uptake by Evaporating pMDI Aerosol Prior to Inhalation Affects Both Regional and Total Deposition in the Respiratory System

As pulmonary drug deposition is a function of aerosol particle size distribution, it is critical that the dynamics of particle formation and maturation in pMDI sprays in the interim between generation and inhalation are fully understood. This paper presents an approach to measure the evaporative and...

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Bibliografiske detaljer

Principais autores:	Victoria Legh-Land, Allen E. Haddrell, David Lewis, Darragh Murnane, Jonathan P. Reid
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2021-06-01
Serier:	Pharmaceutics
Fag:	metered dose inhaler spray plume aging water condensation aerosol hygroscopic growth deposition modelling
Online adgang:	https://www.mdpi.com/1999-4923/13/7/941
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