The Epipeptide YydF Intrinsically Triggers the Cell Envelope Stress Response of Bacillus subtilis and Causes Severe Membrane Perturbations

The Gram-positive model organism and soil bacterium Bacillus subtilis naturally produces a variety of antimicrobial peptides (AMPs), including the ribosomally synthesized and post-translationally modified AMP YydF, which is encoded in the yydFGHIJ locus. The yydF gene encodes the pre-pro-peptide, wh...

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Autori principali:	Philipp F. Popp, Alhosna Benjdia, Henrik Strahl, Olivier Berteau, Thorsten Mascher
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2020-02-01
Serie:	Frontiers in Microbiology
Soggetti:	Bacillus subtilis antimicrobial peptides cell envelope stress response RiPP epipeptide membrane depolarization
Accesso online:	https://www.frontiersin.org/article/10.3389/fmicb.2020.00151/full
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