Recombination junctions from antibody isotype switching classify immune and DNA repair dysfunction

Abstract Personalized assessment of immunocompetence and DNA double-strand break (DSB) repair requires methods that are sensitive to genetic and molecular complexity beyond the well-known monogenic disorders. Inspired by decades of research using B cells to study DNA repair processes, here we presen...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Clara Vázquez García, Benedikt Obermayer, Baerbel Keller, Mikhail Lebedin, Christoph Ratswohl, Hassan Abolhassani, Antonia Busse, Michela Di Virgilio, Stephan Mathas, Dorothee Speiser, Dieter Beule, Qiang Pan-Hammarström, Klaus Warnatz, Kathrin de la Rosa
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Portfolio 2025-12-01
Sarja:	Nature Communications
Linkit:	https://doi.org/10.1038/s41467-025-67206-5
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