A Pathologically Friendly Strategy for Determining the Organ‐specific Spatial Tumor Microenvironment Topology in Lung Adenocarcinoma Through the Integration of snRandom‐seq and Imaging Mass Cytometry

Abstract Heterogeneous organ‐specific responses to immunotherapy exist in lung cancer. Dissecting tumor microenvironment (TME) can provide new insights into the mechanisms of divergent responses, the process of which remains poor, partly due to the challenges associated with single‐cell profiling us...

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Autores principales:	Xuqi Sun, Xiao Teng, Chuan Liu, Weihong Tian, Jinlin Cheng, Shuqiang Hao, Yuzhi Jin, Libing Hong, Yongqiang Zheng, Xiaomeng Dai, Linying Wu, Lulu Liu, Xiaodong Teng, Yi Shi, Peng Zhao, Weijia Fang, Yu Shi, Xuanwen Bao
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2024-07-01
Colección:	Advanced Science
Materias:	lung adenocarcinoma organ‐specific landscapes single‐cell nuclei RNA sequencing spatial topology tumor microenvironments
Acceso en línea:	https://doi.org/10.1002/advs.202308892
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