Mysteries of α1-antitrypsin deficiency: emerging therapeutic strategies for a challenging disease
The classical form of α1-antitrypsin deficiency (ATD) is an autosomal co-dominant disorder that affects ~1 in 3000 live births and is an important genetic cause of lung and liver disease. The protein affected, α1-antitrypsin (AT), is predominantly derived from the liver and has the function of inhib...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2014-04-01
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| Colecção: | Disease Models & Mechanisms |
| Assuntos: | |
| Acesso em linha: | http://dmm.biologists.org/content/7/4/411 |
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