Generation of an immortalized astrocytic cell line from Abcd1-deficient H-2KbtsA58 mice to facilitate the study of the role of astrocytes in X-linked adrenoleukodystrophy

X-linked adrenoleukodystrophy (X-ALD) is an inherited metabolic disease characterized by inflammatory demyelination, and activated astrocytes as well as microglia are thought to be involved in its pathogenesis. Conditionally immortalized astrocytic cell clones were prepared from wild-type or Abcd1-d...

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Detalhes bibliográficos

Principais autores:	Masashi Morita, Ai Toida, Yuki Horiuchi, Shiro Watanabe, Masakiyo Sasahara, Kosuke Kawaguchi, Takanori So, Tsuneo Imanaka
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2021-02-01
coleção:	Heliyon
Assuntos:	Abcd1 Astrocyte Immortalized cell X-linked adrenoleukodystrophy Peroxisome Very long chain fatty acid
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405844021003339
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