Can mutation abundance assess the biological behavior of BRAF V600E-positive papillary thyroid carcinoma?

Abstract Background BRAF V600E mutation is the most common genetic change in papillary thyroid carcinoma (PTC). Nevertheless, the association between BRAF V600E mutation status and abundance and the biological behavior of PTC is unclear. Thus, this study investigated whether BRAF V600E mutation stat...

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Autori principali:	Yeqin Ni, Ping Song, Xiangfeng Lin, Jingjing Shi, Qian Shi, Yuanhui Li, Siyu Zhu, Tianhan Zhou, Yanping Xun, Shirong Zhang, Xingchang Ren, Kaining Lu, Fan Wu, Wei Wang, Pan Zhao, Rongjing Zhou, Wenhua Zhang, Dandan Li, Jiaoping Zhang, Chuanghua Chen, Linlin Mao, Li Zhou, Gang Pan, You Peng, Yunxian Yu, Yuying Chen, Rong Ni, Guhan Luo, Yu Zhang, Jugao Fang, Haitao Zheng, Dingcun Luo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-07-01
Serie:	Journal of Translational Medicine
Soggetti:	Thyroid cancer BRAF V600E mutation abundance Risk stratification Machine learning Clinical decision
Accesso online:	https://doi.org/10.1186/s12967-025-06493-4
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