Pridopidine subtly ameliorates motor skills in a mouse model for vanishing white matter

Assessment of the therapeutic efficacy of 4-PBA, TUDCA, and pridopidine in a vanishing white matter mouse model shows that only pridopidine subtly ameliorates motor skills. The leukodystrophy vanishing white matter (VWM) is characterized by chronic and episodic acute neurological deterioration. Cura...

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Autors principals:	Ellen Oudejans, Diede Witkamp, Gino V Hu-A-Ng, Leoni Hoogterp, Gemma van Rooijen-van Leeuwen, Iris Kruijff, Pleun Schonewille, Zeinab Lalaoui El Mouttalibi, Imke Bartelink, Marjo S van der Knaap, Truus EM Abbink
Format:	Artigo
Idioma:	Inglês
Publicat:	Life Science Alliance LLC 2024-03-01
Col·lecció:	Life Science Alliance
Accés en línia:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202302199
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