Case Report: Unlocking opportunities in HER2-targeted antibody-drug conjugates for bulky leptomeningeal metastatic breast cancer

Leptomeningeal carcinomatosis (LC) is a severe complication of metastatic breast cancer (mBC), with rising incidence. The prognosis for patients with LC has been poor, with a median overall survival of approximately four months. However, recent therapeutic advances, in particular the introduction of...

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Bibliografiske detaljer

Principais autores:	Alessandro Leal, Douglas Kondziolka, Donato Pacione, Stacy Antwi, Sylvia Kurz, Nancy Lin, Sylvia Adams
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2025-08-01
Serier:	Frontiers in Oncology
Fag:	metastatic breast cancer leptomeningeal disease HER2-targeted therapy antibody-drug conjugate trastuzumab deruxtecan
Online adgang:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1559085/full
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