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PD-L1 pfeRNAs as blood-based predictors of treatment response of unresectable malignant pleural mesothelioma patients administered Durvalumab with cisplatin and pemetrexed as first-line therapy

Background: A new therapeutic avenue combining Durvalumab with cisplatin-pemetrexed (Durva-CP) has delivered a promising outcome for previously untreated patients with unresectable malignant pleural mesothelioma (MPM) in clinical trials. However, the limited patient response to Durva-CP needs predic...

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Principais autores: Andrei Gurau, Suguru Yamauchi, Kaitlyn Ecoff, Kristen P. Rodgers, James R. Eshleman, Charles Conover Talbot Jr, Peng Huang, Joshua Choi, Patrick M. Forde, Valsamo Anagnostou, Malcolm Brock, Yuping Mei
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co., Ltd. 2025-06-01
coleção:Non-coding RNA Research
Assuntos:
PD-L1
pfeRNA
MPM
Durvalumab
Pemetrexed
Cisplatin
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2468054025000253
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