Plexin B1 controls Treg numbers, limits allergic airway inflammation, and regulates mucins
We investigated the effect of global Plexin B1 deficiency on allergic airway responses to house dust mite (HDM) or ovalbumin (OVA). In the HDM model, there were higher Th2 cytokine levels in the BALF of Plexin B1 knock-out (KO) mice compared to wild type (WT), and tissue inflammation and mucus produ...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Frontiers Media S.A.
2024-01-01
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| Schriftenreihe: | Frontiers in Immunology |
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| Online-Zugang: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1297354/full |
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