Use of a Multiplexed CMOS Microarray to Optimize and Compare Oligonucleotide Binding to DNA Probes Synthesized or Immobilized on Individual Electrodes

The CombiMatrix microarray with 12,544 electrodes supports in situ electrochemical synthesis of user-defined DNA probes. As an alternative, we immobilized commercially synthesized DNA probes on individual electrodes coated with electropolymerized polypyrrole (Ppy). Hybridization was measured using a...

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Hlavní autoři:	David Danley, Wanda Lyon, John Cooper, Jodi Wilmoth, Nina Yazvenko, Karl Maurer
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2010-08-01
Edice:	Sensors
Témata:	CombiMatrix microarray biosensor electrochemical detection DNA hybridization polypyrrole
On-line přístup:	http://www.mdpi.com/1424-8220/10/8/7371/
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