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Mechanism of Mitophagy to Protect Yak Kidney from Hypoxia-Induced Fibrosis Damage by Regulating Ferroptosis Pathway

Renal fibrosis is a critical pathological feature of various chronic kidney diseases, with hypoxia being recognized as an important factor in inducing fibrosis. Yaks have long inhabited high-altitude hypoxic environments and do not exhibit fibrotic damage under chronic hypoxia. However, the underlyi...

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Principais autores: Xuefeng Bai, Hongqin Lu, Rui Ma, Sijiu Yu, Shanshan Yang, Junfeng He, Yan Cui
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-04-01
Serier:Biomolecules
Fag:
mitophagy
ferroptosis
renal fibrosis
hypoxia adaptation
yak
Online adgang:https://www.mdpi.com/2218-273X/15/4/556
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