LRP1 involvement in FHIT-regulated HER2 signaling in non-small cell lung cancer

The tumor suppressor fragile histidine triad (FHIT) is frequently lost in non-small cell lung cancer (NSCLC). We previously showed that a down-regulation of FHIT causes an up-regulation of the activity of HER2 associated to an epithelial-mesenchymal transition (EMT) and that lung tumor cells harbori...

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Autores principales:	Théophile Ponchel, Emma Loeffler, Julien Ancel, Audrey Brisebarre, Nathalie Lalun, Véronique Dalstein, Anne Durlach, Gaëtan Deslée, Stéphane Dedieu, Myriam Polette, Béatrice Nawrocki-Raby
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2025-03-01
Colección:	European Journal of Cell Biology
Materias:	NSCLC FHIT HER2 LRP1 EMT
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S017193352400092X
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