omnideconv: a unifying framework for using and benchmarking single-cell-informed deconvolution of bulk RNA-seq data

Abstract Background In silico cell-type deconvolution from bulk transcriptomics data is a powerful technique to gain insights into the cellular composition of complex tissues. While first-generation methods used precomputed expression signatures covering limited cell types and tissues, second-genera...

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Үндсэн зохиолчид:	Alexander Dietrich, Lorenzo Merotto, Konstantin Pelz, Bernhard Eder, Constantin Zackl, Katharina Reinisch, Frank Edenhofer, Federico Marini, Gregor Sturm, Markus List, Francesca Finotello
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2026-01-01
Цуврал:	Genome Biology
Нөхцлүүд:	Cell-type deconvolution Transcriptomics Single-cell RNA-seq Bulk RNA-seq Method benchmark Unified method access
Онлайн хандалт:	https://doi.org/10.1186/s13059-026-03955-w
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!