APC/CCDH1 synchronizes ribose-5-phosphate levels and DNA synthesis to cell cycle progression

Ribose-5-phosphate (R5P) is required for DNA synthesis, but how this is regulated during cell cycle progression is unclear. Here the authors report that the cell cycle regulator APC/C-CDH1 synchronizes cell cycle progression with R5P-derived DNA synthesis by controlling TKTL1 stability

Detalhes bibliográficos

Principais autores:	Yang Li, Cui-Fang Yao, Fu-Jiang Xu, Yuan-Yuan Qu, Jia-Tao Li, Yan Lin, Zhong-Lian Cao, Peng-Cheng Lin, Wei Xu, Shi-Min Zhao, Jian-Yuan Zhao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2019-06-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-019-10375-x
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