Dextran-coated Fe3O4 nanoparticles with ratio-dependent drug loading: structural characterization and cytotoxicity in colorectal cancer cells

IntroductionThis study focuses on the development of dextran-coated iron oxide nanoparticles (Fe3O4@Dextran NPs) as carriers for chrysin, a natural flavonoid with recognized anticancer activity.MethodsFe3O4@Dextran NPs were synthesized via co-precipitation and loaded with chrysin at different drug-t...

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Principais autores:	Aynura Karimova, Sabina Hajizada, Habiba Shirinova, Sevinj Nuriyeva, Lala Gahramanli, Aygun Mehdiyeva, Goncha Eyvazova, Toghrul Sadikhov, Natalia Lenz, Inji Nasirova, Christoph Reissfelder, Vugar Yagublu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-09-01
Colecção:	Frontiers in Nanotechnology
Assuntos:	iron oxide nanoparticles dextran coating tumor microenvironment surface modification drug carriers
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnano.2025.1634225/full
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