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Evolutionarily distant I domains can functionally replace the essential ligand-binding domain of Plasmodium TRAP

Inserted (I) domains function as ligand-binding domains in adhesins that support cell adhesion and migration in many eukaryotic phyla. These adhesins include integrin αβ heterodimers in metazoans and single subunit transmembrane proteins in apicomplexans such as TRAP in Plasmodium and MIC2 in Toxopl...

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Príomhchruthaitheoirí: Dennis Klug, Sarah Goellner, Jessica Kehrer, Julia Sattler, Léanne Strauss, Mirko Singer, Chafen Lu, Timothy A Springer, Friedrich Frischknecht
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: eLife Sciences Publications Ltd 2020-07-01
Sraith:eLife
Ábhair:
Rochtain ar líne:https://elifesciences.org/articles/57572
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