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Molecular docking and statistical optimization of taurocholate-stabilized galactose anchored bilosomes for the enhancement of sofosbuvir absorption and hepatic relative targeting efficiency

The work aimed to improve both absorption and hepatic availability of sofosbuvir. Bilosomes and galactose-anchored bilosomes were investigated as potential nanocarriers for this purpose. Sofosbuvir is a class III drug with high solubility and low permeability. Thus, the drug entrapment into lipid-ba...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Marianne Joseph Naguib, Amira Moustafa Kamel, Ahmed Thabet Negmeldin, Ahmed Hassen Elshafeey, Ibrahim Elsayed
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis Group 2020-01-01
Saila:Drug Delivery
Gaiak:
Sarrera elektronikoa:http://dx.doi.org/10.1080/10717544.2020.1787557
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