Protein production in Escherichia coli is guided by the trade-off between intracellular substrate availability and energy cost

Abstract Background In vivo protein formation is a crucial part of cellular life. The process needs to adapt to growth conditions and is exploited for the production of technical and pharmaceutical proteins in microbes such as Escherichia coli. Accordingly, the elucidation of basic regulatory mechan...

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Detalhes bibliográficos

Principais autores:	Alexander Nieß, Martin Siemann-Herzberg, Ralf Takors
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-01-01
coleção:	Microbial Cell Factories
Assuntos:	Translation elongation Heterologous gene expression Codon-adaptation Cell-free protein synthesis Translation optimization
Acesso em linha:	http://link.springer.com/article/10.1186/s12934-019-1057-5
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