PSMC-FAC: Automated Optimization of False-Negative Rate Corrections for Low-Coverage PSMC-Based Demographic Inference

Inferring demographic history from whole-genome data is a central objective in evolutionary and conservation genomics. However, the Pairwise Sequentially Markovian Coalescent (PSMC) framework, one of the most widely used demographic inference methods for whole-genome sequence data, is highly sensiti...

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Principais autores:	Francisco Iglesias-Santos, Alba Nieto, Sònia Casillas, Antonio Barbadilla, Carlos Sarabia
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2026-04-01
Serija:	Biology
Teme:	demographic inference Sequential Markovian Coalescent PSMC Hausdorff distance Fréchet distance low-coverage genome
Online dostop:	https://www.mdpi.com/2079-7737/15/8/631
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