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The Effect of Dextrose Hypotonic vs Saline Hydration on Methotrexate-Induced Nephrotoxicity in Male and Female Rats

Background: High-dose methotrexate (HDMTX) as a cytotoxic agent might cause various side effects. Hyperhydration has been implemented as the major strategy to decrease the potential risk of toxicities induced by HDMTX. This study aims to assess the renoprotective effect of hydration with dextrose wa...

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Principais autores: Zahra Hasanpour, Samira Choopani, Farzaneh Ashrafi, Ardeshir Talebi, Mehdi Nematbaksh
Formato: Artigo
Idioma:Inglês
Publicado: Wolters Kluwer Medknow Publications 2024-02-01
Series:Advanced Biomedical Research
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Acceso en liña:https://journals.lww.com/10.4103/abr.abr_269_22
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