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Immunological Hallmarks for Clinical Response to BCG in Bladder Cancer

Intravesical Bacillus Calmette-Guerin (BCG) is an effective immunotherapy for non-muscle invasive bladder cancer (NMIBC). However, recurrence and progression remain frequent warranting deeper insights into its mechanism. We herein comprehensively profiled blood and tissues obtained from NMIBC patien...

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Hlavní autoři: Chun Jye Lim, Phuong Hoang Diem Nguyen, Martin Wasser, Pavanish Kumar, Yun Hua Lee, Nurul Jannah Mohamed Nasir, Camillus Chua, Liyun Lai, Sharifah Nur Hazirah, Josh Jie Hua Loh, Li Yan Khor, Joe Yeong, Tony Kiat Hon Lim, Alvin Wei Xiang Low, Salvatore Albani, Tsung Wen Chong, Valerie Chew
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021-01-01
Edice:Frontiers in Immunology
Témata:
Bacillus Calmette–Guerin (BCG)
bladder cancer
Immunotherapy
biomarkers
PD-1
On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2020.615091/full
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