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Oncogenic functions of polypyrimidine tract-binding protein 1 in breast cancer metabolism and progression

Polypyrimidine tract-binding protein 1 (PTBP1) is an RNA-binding protein that regulates alternative splicing and primarily acts as a splicing repressor. Previous studies have shown that PTBP1 is closely linked to cancer metabolism through regulation by miR-133b and miR-124, which inhibit PTBP1 expre...

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Wedi'i Gadw mewn:
Prif Awduron: Manabu Futamura, Yoshihisa Tokumaru, Akira Nakakami, Yoshimi Niwa, Junichi Mase, Emiri Sugiyama, Mai Okawa, Kana Matsuda, Ryutaro Mori, Yukihiro Akao, Nobuhisa Matsuhashi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2026-03-01
Cyfres:Biochemistry and Biophysics Reports
Pynciau:
Breast cancer
Glycolysis
PKM
PTBP1
Oncogene
Warburg effect
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S240558082600018X
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