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Broad-Spectrum Small-Molecule Inhibitors of the SARS-CoV-2 Spike—ACE2 Protein–Protein Interaction from a Chemical Space of Privileged Protein Binders

Therapeutically useful small-molecule inhibitors (SMIs) of protein–protein interactions (PPIs) initiating the cell attachment and entry of viruses could provide novel alternative antivirals that act via mechanisms similar to that of neutralizing antibodies but retain the advantages of small-molecule...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sung-Ting Chuang, Peter Buchwald
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2022-08-01
Saila:Pharmaceuticals
Gaiak:
Sarrera elektronikoa:https://www.mdpi.com/1424-8247/15/9/1084
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