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NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma

Abstract Background Increased expression of the transcription factor Forkhead box M1 (FOXM1) has been reported to play an important role in the progression and development of multiple tumors, but the molecular mechanisms that regulate FOXM1 expression remain unknown, and the role of FOXM1 in aerobic...

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Main Authors: Xiangsheng Su, Yihang Yang, Qing Yang, Bo Pang, Shicheng Sun, Yanjun Wang, Qiujiang Qiao, Changfa Guo, Huanting Liu, Qi Pang
Format: Artigo
Language:Inglês
Published: BMC 2021-11-01
Series:BMC Cancer
Subjects:
NOX4
ROS
FOXM1
Aerobic glycolysis
Glioblastoma
Online Access:https://doi.org/10.1186/s12885-021-08933-y
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