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Inhibition of DAGLβ as a therapeutic target for pain in sickle cell disease

Sickle cell disease (SCD) is the most common inherited disease. Pain is a key morbidity of SCD and opioids are the main treatment but their side effects emphasize the need for new analgesic approaches. Humanized transgenic mouse models have been instructive in understanding the pathobiology of SCD...

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Hoofdauteurs: Iryna A. Khasabova, Jacob Gable, Malcolm Johns, Sergey G. Khasabov, Alexander E. Kalyuzhny, Mikhail Y. Golovko, Svetlana A. Golovko, Stacy Kiven, Kalpna Gupta, Virginia S. Seybold, Donald A. Simone
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ferrata Storti Foundation 2022-05-01
Reeks:Haematologica
Online toegang:https://haematologica.org/article/view/10659
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