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Stress induces oxytocin-Gαi-dependent remodeling of astrocytes to shape neuronal response in the amygdala

Abstract Anticipated reactions to stressful situations are vital for the survival and well-being of organisms, and abnormal reactions results in stress-related disorders. The neuropeptide oxytocin is a key modulator ensuring well-adapted stress responses. Oxytocin acts on both neurons and astrocytes...

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Hauptverfasser: Angel Baudon, Valentin Grelot, Kai-Yi Wang, Ferdinand Althammer, Clémence Denis, Pierre Riché-Piotaix, Azmal Syed Ali, Yudong Yan, Fernando Castillo Díaz, Francesca Piacentini, Etienne Clauss Creusot, Volodya Hovhannisyan, Tim Schubert, Annabel C. Kleinwaechter, Eva M. Eisemann, Jabir Aliyu Muhammad, Jemima Helen, Tom Lakomy, Quirin Krabichler, Rachel Breton, Virginie Andry, Maria-Angeles Carrillo-de Sauvage, Valérie Demais, Aurélia Cès, Felix Franke, Franziska Schommer, Mélanie Kremer, Barbara Di Benedetto, Yannick Goumon, Christian P. Schaaf, Valery Grinevich, Nathalie Rouach, Pascal Darbon, Inga D. Neumann, Antoine Adamantidis, Marta Busnelli, Lucile Benhaim, Jeroen Krijgsveld, Frank W. Pfrieger, Alexandre Charlet
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2025-12-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/s41467-025-68114-4
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