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Escherichia coli frameshift mutation rate depends on the chromosomal context but not on the GATC content near the mutation site.

Different studies have suggested that mutation rate varies at different positions in the genome. In this work we analyzed if the chromosomal context and/or the presence of GATC sites can affect the frameshift mutation rate in the Escherichia coli genome. We show that in a mismatch repair deficient b...

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Autors principals: Mariana A Martina, Elisa M E Correa, Carlos E Argaraña, José L Barra
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3306285?pdf=render
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