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Cyclic increase in the ADAMTS1-L1CAM-EGFR axis promotes the EMT and cervical lymph node metastasis of oral squamous cell carcinoma

Abstract The matrix metalloprotease A disintegrin and metalloprotease with thrombospondin motifs 1 (ADAMTS1) was reported to be involved in tumor progression in several cancer types, but its contributions appear discrepant. At present, the role of ADAMTS1 in oral squamous cell carcinoma (SCC; OSCC)...

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Autori principali: Ming-Hsien Chien, Yi-Chieh Yang, Kuo-Hao Ho, Yi-Fang Ding, Li-Hsin Chen, Wen-Kuan Chiu, Ji-Qing Chen, Min-Che Tung, Michael Hsiao, Wei-Jiunn Lee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2024-01-01
Serie:Cell Death and Disease
Accesso online:https://doi.org/10.1038/s41419-024-06452-9
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