Bidirectional two-sample mendelian randomization analysis identifies causal associations of MRI-based cortical thickness and surface area relation to NAFLD

Abstract Background Non-alcoholic fatty liver disease (NAFLD) patients have exhibited extra-hepatic neurological changes, but the causes and mechanisms remain unclear. This study investigates the causal effect of NAFLD on cortical structure through bidirectional two-sample Mendelian randomization an...

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Bibliografski detalji

Glavni autori:	Zun Mao, Zhi-xiang Gao, Tong Ji, Sheng Huan, Guo-ping Yin, Long Chen
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2024-02-01
Serija:	Lipids in Health and Disease
Teme:	GWAS NAFLD Cortical structure Brain-liver axis
Online pristup:	https://doi.org/10.1186/s12944-024-02043-x
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