Active PD-L1 incorporation within HIV virions functionally impairs T follicular helper cells.

The limited development of broadly neutralizing antibodies (BnAbs) during HIV infection is classically attributed to an inadequate B-cell help brought by functionally impaired T follicular helper (Tfh) cells. However, the determinants of Tfh-cell functional impairment and the signals contributing to...

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Bibliographic Details

Main Authors:	Olivia Munoz, Riddhima Banga, Rachel Schelling, Francesco Andrea Procopio, Andrea Mastrangelo, Pauline Nortier, Khalid Ohmiti, Jean Daraspe, Matthias Cavassini, Craig Fenwick, Laurent Perez, Matthieu Perreau
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science (PLoS) 2022-07-01
Series:	PLoS Pathogens
Online Access:	https://doi.org/10.1371/journal.ppat.1010673
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