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Breast cancer risk genes affecting individual radiosensitivity

Abstract Increased radiosensitivity can cause adverse radiotherapy effects. Heterozygote variants in breast cancer risk genes increase cancer risk and may affect radiosensitivity. This study assessed their impact on individual radiosensitivity to determine the radiation risk for gene carriers. Radio...

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Enregistré dans:
Auteurs principaux: Ramona K. G. Vogel, Niklas Amann, Tara Zuhair Kassem, Paul Gaß, Theresa Mayo, Felix Woltereck, Carolin C. Hack, Rainer Fietkau, Stefanie Corradini, Luitpold Distel, Lukas C. F. Kuhlmann
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2026-06-01
Collection:Scientific Reports
Sujets:
Breast cancer risk genes
Radiosensitivity
BRCA1
BRCA2
Fluorescence in situ hybridization
Chromosomal aberrations
Accès en ligne:https://doi.org/10.1038/s41598-026-57275-x
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