Comparative pharmacokinetics of porcine and human anti-influenza hemagglutinin monoclonal antibodies in outbred pigs and minipigs

Assessing the pharmacokinetics of monoclonal antibodies (mAbs) in relevant animal models is essential for designing improved formulations and developing mAb delivery platforms. We have established the pig, a large natural host animal for influenza with many similarities to humans, as a robust model...

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Váldodahkkit:	Basudev Paudyal, Elliot Moorhouse, Bhawna Sharma, Michael Dodds, Victor Nguyen, Mark Milad, Elma Tchilian
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2024-10-01
Ráidu:	Frontiers in Immunology
Fáttát:	pharmacokinetic anti-influenza monoclonal antibodies minipigs outbred pigs 2-12C pb27
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1471412/full
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