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Integrating In Silico and In Vitro Tools for Optimized Antibody Development—Design of Therapeutic Anti-oxMIF Antibodies

Background: Rigorous assessment of antibody developability is crucial for optimizing lead candidates before progressing to clinical studies. Recent advances in predictive tools for protein structures, surface properties, stability, and immunogenicity have streamlined the development of new biologics...

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Autors principals: Gregor Rossmueller, Irina Mirkina, Michael Thiele, Alejandro Puchol Tarazona, Florian Rueker, Randolf J. Kerschbaumer, Alexander Schinagl
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2024-12-01
Col·lecció:Antibodies
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Accés en línia:https://www.mdpi.com/2073-4468/13/4/104
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