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Preferential transmission of minority and drug-resistant clones in polyclonal infections in Mali

Abstract Background In polyclonal human malaria infections, the roles of individual clones in human-to-mosquito transmission and their relative transmissibility remain poorly understood. In addition, mutations conferring drug resistance can result in a transmission advantage or disadvantage. Methods...

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Asıl Yazarlar: Leen N. Vanheer, Emilia Manko, Almahamoudou Mahamar, Jody Phelan, Koualy Sanogo, Youssouf Sinaba, Sidi M. Niambele, Adama Sacko, Sekouba Keita, Ahamadou Youssouf, Makonon Diallo, Harouna M. Soumare, Kjerstin Lanke, Djibrilla Issiaka, Halimatou Diawara, Sekou F. Traore, Lynn Grignard, Alassane Dicko, Chris Drakeley, Susana Campino, William Stone
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2025-04-01
Seri Bilgileri:Malaria Journal
Konular:
Malaria
Plasmodium falciparum
Gametocytes
Transmission
Comparative genomics
Genetic diversity
Online Erişim:https://doi.org/10.1186/s12936-025-05298-6
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