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Predicting overlapping protein complexes based on core-attachment and a local modularity structure

Abstract Background In recent decades, detecting protein complexes (PCs) from protein-protein interaction networks (PPINs) has been an active area of research. There are a large number of excellent graph clustering methods that work very well for identifying PCs. However, most of existing methods us...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Rongquan Wang, Guixia Liu, Caixia Wang, Lingtao Su, Liyan Sun
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2018-08-01
Schriftenreihe:BMC Bioinformatics
Schlagworte:
Protein-protein interaction networks
Protein complex
Overlapping node
Seed-extension paradigm
Core-attachment and local modularity structure
Node betweenness
Online-Zugang:http://link.springer.com/article/10.1186/s12859-018-2309-9
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