No synergism between bis(propyl)-cognitin and rasagiline on protecting dopaminergic neurons in Parkinson's disease mice

Rasagiline, a monoamine oxidase-B inhibitor, and bis(propyl)-cognitin (B3C), a novel dimer are reported to be neuroprotective. Herein, the synergistical neuroprotection produced by rasagiline and B3C was investigated in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mice of Parkinsonism...

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Detalhes bibliográficos

Principais autores:	Cheng-you Zheng, Bao-jian Guo, Wei Cai, Wei Cui, Shing-hung Mak, Yu-qiang Wang, Simon Ming-yuen Lee, Yi-fan Han, Zai-jun Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wolters Kluwer Medknow Publications 2016-01-01
coleção:	Neural Regeneration Research
Assuntos:	nerve regeneration; Parkinson′s disease; bis(propyl)-cognitin; rasagiline; monoamine oxidase B; dopamine; multitarget; synergism; neuroprotection; neural regeneration
Acesso em linha:	http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=8;spage=1339;epage=1346;aulast=Zheng
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