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In vivo Emergence of Colistin and Tigecycline Resistance in Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae During Antibiotics Treatment

Three carbapenem-resistant Klebsiella pneumoniae (CRKP; strains KP-426, KP-C76, and KP-CT77) were isolated from a patient with severe burns during the treatment of colistin and tigecycline. Single-nucleotide polymorphism typing showed that three ST11 CRKP were clonally related. Three isolates harbor...

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Principais autores: Jiawei Chen, Yu Zeng, Rong Zhang, Jiachang Cai
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-09-01
Serier:Frontiers in Microbiology
Fag:
carbapenem-resistant hypervirulent Klebsiella pneumonia
colistin resistance
mgrB
tigecycline resistance
tet(A)
Online adgang:https://www.frontiersin.org/articles/10.3389/fmicb.2021.702956/full
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