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BosR functions as a repressor of the ospAB operon in Borrelia burgdorferi.

The Lyme disease spirochete, Borrelia burgdorferi, must abundantly produce outer surface lipoprotein A (OspA) in the tick vector but downregulate OspA in mammals in order to evade the immune system and maintain its natural enzootic cycle. Here, we show that BosR binds two regulatory elements of the...

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Bibliografiske detaljer
Principais autores: Yanlin Shi, Poonam Dadhwal, Xin Li, Fang Ting Liang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2014-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC4182837?pdf=render
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