High-yield isolation and characterization of microvascular niche cells from human full-thickness skin biopsies

Abstract The development of physiologically relevant in vitro vascular models requires access to the cellular components of the microvascular niche. However, most studies rely on a limited subset of vascular or support cells, often using pooled, immortalized, or non-adult sources. To address this li...

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Principais autores:	A. Uccelli, M. Cenciarini, V. Colombo, C. Zamboni, D. Valentino, Y. Harder, C. Arrigoni, M. Moretti, S. Bersini
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2026-04-01
Series:	Scientific Reports
Assuntos:	Microvascular niche Cell isolation protocol Human dermal vasculature Donor-matched 3D microvascular models
Acceso en liña:	https://doi.org/10.1038/s41598-026-49055-4
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