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Detection of <i>CTNNB1</i> Hotspot Mutations in Cell-Free DNA from the Urine of Hepatocellular Carcinoma Patients

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide. The beta-catenin gene, <i>CTNNB1,</i> is among the most frequently mutated in HCC tissues. However, mutational analysis of HCC tumors is hampered by the difficulty of obtaining tissue samples using traditional biop...

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Hoofdauteurs: Selena Y. Lin, Ting-Tsung Chang, Jamin D. Steffen, Sitong Chen, Surbhi Jain, Wei Song, Yih-Jyh Lin, Ying-Hsiu Su
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2021-08-01
Reeks:Diagnostics
Onderwerpen:
hepatocellular carcinoma
cell-free DNA
beta-catenin
urine
mutation
recurrence
Online toegang:https://www.mdpi.com/2075-4418/11/8/1475
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