Peripheral Dopamine Directly Acts on Insulin-Sensitive Tissues to Regulate Insulin Signaling and Metabolic Function

Dopamine is a key regulator of glucose metabolism in the central nervous system. However, dopamine is also present in the periphery and may have direct effects on insulin-sensitive tissues. Dopamine receptor 2 (D2R) agonist bromocriptine is a FDA-approved drug for type 2 diabetes. Herein, we explore...

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Principais autores:	Gabriela Tavares, Fatima. O. Martins, Bernardete. F. Melo, Paulo Matafome, Silvia. V. Conde
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-09-01
coleção:	Frontiers in Pharmacology
Assuntos:	dopamine insulin signaling glucose metabolism lipid metabolism D1 dopamine receptor D2 dopamine receptor
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2021.713418/full
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