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Methylation of CYP1A1 and VKORC1 promoter associated with stable dosage of warfarin in Chinese patients

Objective To investigate the association between DNA methylation and the stable warfarin dose through genome-wide DNA methylation analysis and pyrosequencing assay. Method This study included 161 patients and genome-wide DNA methylation analysis was used to screen potential warfarin dose-associated...

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Principais autores: Shiwei He, Yuan Wu, Shuidi Yan, Jumei Liu, Li Zhao, Huabin Xie, Shengxiang Ge, Huiming Ye
Formato: Artigo
Idioma:Inglês
Publicado: PeerJ Inc. 2021-06-01
Series:PeerJ
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Acceso en liña:https://peerj.com/articles/11549.pdf
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