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Peri-adolescent bupropion treatment alters adult operant responding and is associated with reduced ΔFosB and thin spine density in the nucleus accumbens in rats

Exposure to pharmacological agents can disrupt brain development, producing maladaptive neurobehavioural output. The reward system is established over a protracted developmental time period which allows for age-specific vulnerabilities to external influence. Bupropion (BUP) inhibits dopamine (DA) an...

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Bibliografiske detaljer
Principais autores: Shannon N. Smith, Matthew R. Holahan
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-09-01
Serier:Brain Research Bulletin
Fag:
Online adgang:http://www.sciencedirect.com/science/article/pii/S0361923025002540
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