ASB7 promotes osteosarcoma lung metastasis through ubiquitin-mediated degradation of ATF2

Abstract Osteosarcoma is a highly heterogeneous and aggressive malignancy with a strong propensity for metastasis, highlighting the need to define its molecular drivers. Here, we report that ASB7 promotes tumor cell protrusion formation, invasion, migration, and lung metastasis. High expression of A...

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Bibliografiske detaljer

Principais autores:	Yezi Zou, Jianliang Zhong, Lanqing Huo, Jiali Chen, Xinhao Yu, Jingxuan Wang, Zhenxuan Chen, Lifeng Yin, Cuiling Zeng, Xia Zhang, Shan Han, Ruhua Zhang, Xing-Ding Zhang, Tiebang Kang, Liwen Zhou
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2026-05-01
Serier:	Cell Discovery
Online adgang:	https://doi.org/10.1038/s41421-026-00890-9
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