Molecular determinants of regulatory T cell development: the essential roles of epigenetic changes
Regulatory T (Treg) cells constitute a distinct T cell subset, which plays a key role in immune tolerance and homeostasis. The transcription factor Foxp3 controls a substantial part of Treg cell development and function. Yet its expression alone is insufficient for conferring developmental and funct...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2013-05-01
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| Serie: | Frontiers in Immunology |
| Soggetti: | |
| Accesso online: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00106/full |
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